SPRAVATO®

For people who’ve done the work, tried the meds, and are still waiting for relief. 

For people who’ve done the work, tried the meds, and are still waiting for relief. 

Spravato® Referral Form
Spravato® Referral Form
Patient Screening Form
Patient Screening Form

Spravato® (esketamine) is an FDA-approved nasal spray used to help adults living with treatment-resistant depression. It is self-administered in our office under the supervision of a certified provider.

Unlike most antidepressants, Spravato works by targeting the brain's glutamate system instead of primarily affecting serotonin. This different approach has made it an important option for people who continue to struggle despite trying traditional antidepressants. Clinical studies found that some patients experienced improvement as early as 24 hours.

What is Spravato®?

It may be right for you if:

  • You've tried multiple antidepressants with limited or no improvement.

  • Depression continues to interfere with your daily life despite treatment.

  • You're seeking options that go beyond traditional medications.

During your consultation, we'll take the time to understand your history, discuss your goals, and help guide you toward the treatment approach that's the best fit for you.

RAPID RELIEF

INSURANCE COVERED

FDA-APPROVED

Spravato Treatment Process

1

Initial Consultation

You’ll meet with one of our providers to discuss your history, symptoms, and previous treatment experiences. Together, you will discuss your questions, talk through your options, and determine whether Spravato is an appropriate next step for you.

2

Benefits Verification

Before treatment begins, our team will work with your insurance to verify your benefits, obtain any required authorization, and make sure you are enrolled in Spravato’s copay savings program.

3

Induction Phase

Weeks 1-4
Twice Weekly Appointments

4

Maintenance Phase

Weeks 5-8
Once Weekly Appointments

5

Treatment Optimization

Weeks 9+
Treatment frequency is based on patient needs and response

FAQs

  • Each session lasts about 2.5 hours. 

    You'll self-administer the nasal spray under the supervision of a trained clinician.

    We’ll monitor your blood pressure, heart rate, and response throughout.

    You’ll rest in a calm environment and won’t be allowed to leave until the observation period ends.

    You must arrange a ride home — driving is not permitted until the next day.

  • Weeks 1–4: Twice per week.

    Weeks 5–8: Once per week.

    Week 9 and beyond: Every 1–2 weeks depending on your response. This may vary based on individual needs and your provider’s recommendations.

  • Most commercial insurance plans and Medicare cover Spravato®, but prior authorization is usually required. Our team will guide you through the insurance process and support you with any paperwork or specialty pharmacy coordination needed.

  • Side effects can include:

    • Dizziness or nausea

    • Dissociation or feeling disconnected

    • Increased blood pressure

    • Sleepiness or fatigue

    These are usually temporary and closely monitored at every visit.

  • Not always. If you’re already seeing a mental health provider, we’ll request records or coordinate care with them. If you’re new to treatment, we can provide a psychiatric evaluation to assess your options, including Spravato®.

  • This varies by individual. Some continue for several months while others taper off. Your treatment plan will evolve based on your response, needs, and goals.

  • You’ll need the rest of the day off. We recommend avoiding work, driving, or major decisions until the next day.

What to Expect During Your SPRAVATO® Treatment